Burns
Volume 31, Issue 7 , Pages 855-858 , November 2005

A basic fibroblast growth factor improved the quality of skin grafting in burn patients

  • Sadanori Akita

      Affiliations

    • Division of Plastic and Reconstructive Surgery, Department of Developmetal and Reconstructive Medicine, Nagasaki University, Graduate School of Biomedical and Sciences, 1-7-1 Sakamoto machi, Nagasaki 8528501, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 95 849 7327; fax: +81 95 849 7330.
    • ,
  • Kozo Akino

      Affiliations

    • Division of Anatomy and Neurobiology, Department of Developmental and Reconstructive Medicine, Nagasaki University, Graduate School of Biomedical and Sciences, 1-7-1 Sakamoto machi, Nagasaki 8528501, Japan
    • ,
  • Toshifumi Imaizumi

      Affiliations

    • Division of Plastic and Reconstructive Surgery, Department of Developmetal and Reconstructive Medicine, Nagasaki University, Graduate School of Biomedical and Sciences, 1-7-1 Sakamoto machi, Nagasaki 8528501, Japan
    • ,
  • Akiyoshi Hirano

      Affiliations

    • Division of Plastic and Reconstructive Surgery, Department of Developmetal and Reconstructive Medicine, Nagasaki University, Graduate School of Biomedical and Sciences, 1-7-1 Sakamoto machi, Nagasaki 8528501, Japan

,Accepted 5 April 2005.

References 

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  2. Fujii T. Local treatment for extensive deep dermal thickness burn and follow-up study. Acta Chir Plast. 1990;32:46–56
  3. Zhang K, Garner W, Cohen L, Rodriguez J, Phan S. Increased types I and III collagen and transforming growth factor-beta 1 mRNA and protein in hypertrophic burn scar. J Invest Dermatol. 1995;104:750–754
  4. Nedelec B, Shankowsky H, Scott PG, Ghahary A, Tredget EE. Myofibroblasts and apoptosis in human hypertrophic scars: the effect of interferon-alpha2b. Surgery. 2001;130:798–808
  5. Xue H, McCauley RL, Zhang W, Martini DK. Altered interleukin-6 expression in fibroblasts from hypertrophic burn scars. J Burn Care Rehabil. 2000;21:142–146
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  7. Akino K, Mineta T, Fukui M, Fujii T, Akita S. Bone morphogenetic protein-2 regulates proliferation of human mesenchymal stem cells. Wound Repair Regen. 2003;11:354–360
  8. Nakagawa H, Akita S, Fukui M, Fujii T, Akino K. Human mesenchymal stem cells successfully improve skin-substitute wound healing. Br J Dermatol. 2005;153:29–36
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  12. Atiyeh BS, Amm CA, El Musa KA. Improved scar quality following primary and secondary healing of cutaneous wounds. Aesthetic Plast Surg. 2003;27:411–417
  13. Barret JP, Herndon DN. Effects of burn wound excision on bacterial colonization and invasion. Plast Reconstr Surg. 2003;111:744–750
  14. Xiao-Wu W, Herndon DN, Spies M, Sanford AP, Wolf SE. Effects of delayed wound excision and grafting in severely burned children. Arch Surg. 2002;137:1049–1054
  15. Fu X, Shen Z, Chen Y, Xie J, Guo Z, Zhang M, et al. Randomised placebo-controlled trial of use of topical recombinant bovine basic fibroblast growth factor for second-degree burns. Lancet. 1998;352:1661–1664
  16. Garner WL. Epidermal regulation of dermal fibroblast activity. Plast Reconstr Surg. 1998;102:135–139
  17. Bhora FY, Dunkin BJ, Batzri S, et al. Effect of growth factors on cell proliferation and epithelialization in human skin. J Surg Res. 1995;59:236–244
  18. Hebda PA, Klingbeil CK, Abraham JA, Fiddes JC. Basic fibroblast growth factor stimulation of epidermal wound healing in pigs. J Invest Dermatol. 1990;95:626–631
  19. Hakuba N, Taniguchi M, Shimizu Y, Sugimoto A, Shinomori Y, Gyo K. A new method for closing tympanic membrane perforations using basic fibroblast growth factor. Laryngoscope. 2003;113:1352–1355

PII: S0305-4179(05)00126-9

doi: 10.1016/j.burns.2005.04.008

Burns
Volume 31, Issue 7 , Pages 855-858 , November 2005

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