Burns
Volume 31, Issue 7 , Pages 838-844 , November 2005

Changes of occludin expression in intestinal mucosa after burn in rats

  • Lijian Shao

      Affiliations

    • Department of Human Anatomy, Jiangxi Medical College, No. 603, BaYi Road, Nanchang 330006, Jiangxi, PR China
    • Corresponding Author InformationCorresponding author. Tel.: +86 791 6360557; fax: +86 791 8160381.
    • ,
  • Qiren Huang

      Affiliations

    • Department of Pharmacology, Jiangxi Medical College, Nanchang 330006, PR China
    • ,
  • Ming He

      Affiliations

    • Department of Pharmacology, Jiangxi Medical College, Nanchang 330006, PR China
    • ,
  • Huihong Zeng

      Affiliations

    • Department of Histology and Embryology, Jiangxi Medical College, Nanchang 330006, PR China
    • ,
  • Lidan Wan

      Affiliations

    • Department of Human Anatomy, Jiangxi Medical College, No. 603, BaYi Road, Nanchang 330006, Jiangxi, PR China
    • ,
  • Qingxian Zhu

      Affiliations

    • Department of Histology and Embryology, Jiangxi Medical College, Nanchang 330006, PR China

References 

  1. Hollander D. The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn's disease. Scand J Gastroenterol. 1992;27:721–726
  2. Carter EA, Tompkins RG, Schiffrin E, Burke JF. Cutaneous thermal injury alters macromolecular permeability of rat small intestine. Surgery. 1990;107:335–341
  3. Gonzalez-Mariscal L, Betanzos A, Nava P, Jaramillo BE. Tight junction proteins. Progress Biophys Mol Biol. 2003;81:1–44
  4. Van Itallie CM, Anderson JM. Occludin confers adhesiveness when expressed in fibroblasts. J Cell Sci. 1997;110:1121–1131
  5. Chen YH, Merzdorf C, Paul DC, et al. COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. J Cell Biol. 1997;138:891–899
  6. Jepson MA. Disruption of epithelial barrier function by H2O2: distinct responses of Caco-2 and Madin-Darby canine kidney (MDCK) strains. Cell Mol Biol. 2003;49:101–112
  7. Epstein MD, Tchervenkov JI, Alexander JW, et al. Increased gut permeability following burn trauma. Arch Surg. 1991;126:198–200
  8. Zhang C, Sheng Z-Y, Hu S, et al. The influence of apoptosis of mucosal epithelial cells on intestinal barrier integrity after scald in rats. Burns. 2002;28:731–737
  9. Furuse M, Hirase T, Itoh M, et al. Occludin: a novel integral membrane protein localizing at tight junction. J Cell Biol. 1993;123:1777–1788
  10. Yuhko AA, Saitou M, Hirase T, et al. Inter species diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. J Cell Biol. 1996;133:43–47
  11. McCarthy KM, Skare IB, Stankewich MC, et al. Occludin is a function component of the tight junction. J Cell Sci. 1996;109:2287–2298
  12. Bamforth SD, Kniesel U, Wolburg H, et al. A dominant mutant of occludin disrupts tight junction structure and function. J Cell Sci. 1999;112:1879–1888
  13. Xia G, Martin AE, Michalsky MP, et al. Heparin-binding EGF-like growth factor preserves crypt cell proliferation and decreases bacterial translocation after intestinal ischemia/reperfusion injury. J Pediatr Surg. 2002;37:1081–1087
  14. Ma TY, Iwamoto GK, Hoa NT, et al. TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation. Am J Physiol Gastrointest Liver Physiol. 2004;286:G367–G376
  15. Deitch EA, Specian RD, Berg RD. Endotoxin-induced bacterial translocation and mucosal permeability: role of xanthine oxidase, complement activation, and macrophage products. Crit Care Med. 1991;19:785–791
  16. Sakakibara A, Furuse M, Saitou M, et al. Possible involvement of phosphorylation of occluding in tight junction formation. J Cell Biol. 1997;137:1393–1401
  17. Wong V. Phosphorylation of occludin correlates with occludin localization and function at the tight junction. Am J Physiol. 1997;273:C1859–C1867
  18. Nunbhakdi-Craig V, Craig L, Machleidt T, Sontag E. Simian virus 40 small tumor antigen induces deregulation of the actin cytoskeleton and tight junctions in kidney epithelial cells. J Virol. 2003;77:2807–2818
  19. Tobioka H, Isomura H, Kokai Y, Tokunaga Y, Yamaguchi J, Sawada N. Occludin expression decreases with the progression of human endometrial carcinoma. Hum Pathol. 2004;35:159–164
  20. Tokunaga Y, Tobioka H, Isomura H, Kokai Y, Sawada N. Expression of occludin in human rectal carcinoid tumours as a possible marker for glandular differentiation. Histopathology. 2004;44:247–250
  21. Kucharzik T, Chen SVJ, Parkos CA, Nusrat A. Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteins. Am J Pathol. 2001;159:2001–2009
  22. Takakuwa Y, Kokai Y, Sasaki K, et al. Bile canalicular barrier function and expression of tight-junctional molecules in rat hepatocytes during common bile duct ligation. Cell Tissue Res. 2002;307:181–189

PII: S0305-4179(05)00153-1

doi: 10.1016/j.burns.2005.05.005

Burns
Volume 31, Issue 7 , Pages 838-844 , November 2005

Article Tools

* Image Usage & Resolution