Burns
Volume 33, Issue 1 , Pages 100-104 , February 2007

Delayed reepithelialization and scarring deregulation following drug-induced toxic epidermal necrolysis

  • P. Paquet

      Affiliations

    • Department of Dermatopathology, University Hospital Sart Tilman, CHU, Sart Tilman, B-4000, Liège, Belgium
    • Corresponding Author InformationCorresponding author. Tel.: +32 4 3662408; fax: +32 4 3662976.
    • ,
  • E. Jacob

      Affiliations

    • Intensive Care Department, University Hospital Sart Tilman, Liège, Belgium
    • ,
  • P. Quatresooz

      Affiliations

    • Department of Dermatopathology, University Hospital Sart Tilman, CHU, Sart Tilman, B-4000, Liège, Belgium
    • ,
  • D. Jacquemin

      Affiliations

    • Burn Center, Department of Plastic Surgery, University Hospital Sart Tilman, Liège, Belgium
    • ,
  • G.E. Piérard

      Affiliations

    • Department of Dermatopathology, University Hospital Sart Tilman, CHU, Sart Tilman, B-4000, Liège, Belgium

,Accepted 26 April 2006.

References 

  1. Fritsch PO, Sidoroff A. Drug-induced Stevens-Johnson syndrome/toxic epidermal necrolysis. Am J Clin Dermatol. 2000;1:349–360
  2. Paquet P, Paquet F, Al Saleh W, Reper P, Vanderkelen A, Pierard GE. Immunoregulatory effector cells in drug-induced toxic epidermal necrolysis. Am J Dermatopathol. 2000;22:413–417
  3. Lim IJ, Phan TT, Bay BH, Qi R, Huynh H, Tan WT, et al. Fibroblasts cocultured with keloid keratinocytes: normal fibroblasts secrete collagen in a keloid like manner. Am J Physiol Cell Physiol. 2002;283:C212–C222
  4. Gabbiani G. The myofibroblast in wound healing and fibrocontractive diseases. J Pathol. 2003;200:500–503
  5. Quatresooz P, Henry F, Paquet P, Pierard-Franchimont C, Harding K, Pierard GE. Deciphering the impaired cytokine cascades in chronic leg ulcers. Int J Mol Med. 2003;11:411–418
  6. Machesney M, Tidman N, Waseem A, Kirby L, Leigh I. Activated keratinocytes in the epidermis of hypertrophic scars. Am J Pathol. 1998;152:1133–1141
  7. Boyce DE, Ciampolini J, Ruge F, Murison MS, Harding KG. Inflammatory cell subpopulations in keloid scars. Br J Plast Surg. 2001;54:511–516
  8. Lim IJ, Phan TTP, Song C. Investigation of the influence of keloid-derived keratinocytes on fibroblast growth and proliferation in vitro. Plast Reconstr Surg. 2001;107:797–808
  9. Niessen FB, Spauwen PH, Schalkwijk , Kon M. On the nature of hypertrophic scars and keloids: a review. Plast Reconstr Surg. 1999;105:1435–1458
  10. Funayama E, Chodon T, Oyama A, Sugihara T. Keratinocytes provide proliferation and inhibit apoptosis of the underlying fibroblasts: an important role in the pathogenesis of keloid. J Invest Dermatol. 2003;121:1326–1331
  11. Hermanns-Lê T, Piérard GE. Factor XIIIa-positive dendrocyte rarefaction in Ehlers-Danlos syndrome, classic type. Am J Dermatopathol. 2001;23:427–430
  12. Quatresooz P, Hermanns-Lê T, Ciccarelli A, Beckers A, Pierard GE. Tensegrity and type I dermal dendrocytes in acromegaly. Eur J Clin Invest. 2005;35:133–139
  13. Hermanns-Lê T, Paquet P, Piérard-Franchimont C, Arrese JE, Piérard GE. Regulatory function of factor XIIIa-positive dendrocytes in incipient toxic epidermal necrolysis and graft-versus-host reaction. Dermatology. 1999;198:184–186
  14. Kavanagh GM, Page P, Hanna MM. Silicone gel treatment of extensive hypertrophic scarring following toxic epidermal necrolysis. Br J Dermatol. 1994;130:540–541
  15. Bhashan M, Brooke R, Hewitt-Symond SM, et al. Prolonged toxic epidermal necrolysis due to lamotrigine. Clin Exp Dermatol. 2000;25:349–354
  16. Paquet P, Vanderkelen A, Gielen V, Lapière ChM. The skin equivalent: its use in vivo. Cytotechnology. 1989;50:S47–S53
  17. Burd A, Chan E. Keratinocyte-keloid interaction. Plast Reconstr Surg. 2002;110:197–202
  18. Klein L, Mericka P, Strakova H, Jebavy L, Nozickova M, Blaha M, et al. Biological skin covers in treatment of two cases of the Lyell's syndrome. Ann Transplant. 1997;2:45–48
  19. Paquet P, Quatresooz P, Braham C, Piérard GE. Tapping into the influence of keratinocyte allografts and biocenosis on healing of chronic leg ulcers: split-ulcer controlled pilot study. Dermatol Surg. 2005;31:431–435

PII: S0305-4179(06)00159-8

doi: 10.1016/j.burns.2006.04.031

Burns
Volume 33, Issue 1 , Pages 100-104 , February 2007

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