Burns
Volume 33, Issue 1 , Pages 52-58 , February 2007

The effect of treating infected skin grafts with Acticoat™ on immune cells

  • Vera C. Mazurak

      Affiliations

    • Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alta., Canada T6G 2P5
    • Corresponding Author InformationCorresponding author. Tel.: +1 780 492 8048; fax: +1 780 492 4265.
    • ,
  • Robert E. Burrell

      Affiliations

    • Department of Biomedical Engineering, University of Alberta, Edmonton, Alta., Canada
    • Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Alta., Canada
    • ,
  • Edward E. Tredget

      Affiliations

    • Department of Surgery, Division of Plastic Surgery and Critical Care, University of Alberta, Edmonton, Alta., Canada
    • ,
  • M. Thomas Clandinin

      Affiliations

    • Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alta., Canada T6G 2P5
    • Department of Medicine, University of Alberta, Edmonton, Alta., Canada
    • ,
  • Catherine J. Field

      Affiliations

    • Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alta., Canada T6G 2P5
    • Department of Medicine, University of Alberta, Edmonton, Alta., Canada

,Accepted 25 April 2006.

  • Image Result

    Effect of surgery (Surgery-Noninoculated), surgery+infection (Surgery-Inoculated) and infection+Acticoat (Surgery-Inoculated-Acticoat) on guinea pig splenocyte natural killer cell cytotoxicity determi

    Effect of surgery (Surgery-Noninoculated), surgery+infection (Surgery-Inoculated) and infection+Acticoat (Surgery-Inoculated-Acticoat) on guinea pig splenocyte natural killer cell cytotoxicity determined by a [51Cr] release assay expressed in percent specific lysis and determined by the formula: [(experimental lysis−spontaneous lysis)/(maximum lysis−spontaneous lysis)]×100. Points represent mean±S.E.M. (Surgery-Noninoculated (n=8); Surgery-Inoculated (n=8); Nonsurgery Control (n=6); Surgery-Inoculated-Acticoat (n=6)) at the effector:target ratio indicated. Points that do not share a common superscript are significantly different (p<0.05) as determined by a repeated measures one-way ANOVA and least square means.

PII: S0305-4179(06)00162-8

doi: 10.1016/j.burns.2006.04.027

Burns
Volume 33, Issue 1 , Pages 52-58 , February 2007

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