Burns
Volume 36, Issue 2 , Pages 261-269 , March 2010

Thiamine supplementation increases serum thiamine and reduces pyruvate and lactate levels in burn patients

  • Sian Falder

      Affiliations

    • The McComb Research Foundation, Perth, WA, Australia
    • Royal Perth Hospital, Perth, WA, Australia
    • ,
  • Robyn Silla

      Affiliations

    • The McComb Research Foundation, Perth, WA, Australia
    • Royal Perth Hospital, Perth, WA, Australia
    • ,
  • Michael Phillips

      Affiliations

    • Western Australian Institute for Medical Research, University of Western Australia, Perth, WA, Australia
    • Royal Perth Hospital, Perth, WA, Australia
    • ,
  • Suzanne Rea

      Affiliations

    • The McComb Research Foundation, Perth, WA, Australia
    • Royal Perth Hospital, Perth, WA, Australia
    • Princess Margaret Hospital for Children, Perth, WA, Australia
    • ,
  • Reuven Gurfinkel

      Affiliations

    • Royal Perth Hospital, Perth, WA, Australia
    • Princess Margaret Hospital for Children, Perth, WA, Australia
    • ,
  • Esther Baur

      Affiliations

    • The McComb Research Foundation, Perth, WA, Australia
    • ,
  • Anthony Bartley

      Affiliations

    • The McComb Research Foundation, Perth, WA, Australia
    • Royal Perth Hospital, Perth, WA, Australia
    • ,
  • Fiona M. Wood

      Affiliations

    • The McComb Research Foundation, Perth, WA, Australia
    • Royal Perth Hospital, Perth, WA, Australia
    • Princess Margaret Hospital for Children, Perth, WA, Australia
    • School of Pediatrics, University of Western Australia, Perth, WA, Australia
    • ,
  • Mark W. Fear

      Affiliations

    • The McComb Research Foundation, Perth, WA, Australia
    • Corresponding Author InformationCorresponding author at: The McComb Foundation, Telstra Burn Outcome Centre, 11th floor, Royal Perth Hospital, Wellington Street, Perth, WA 6000, Australia. Tel.: +61 8 9224 3567; fax: +61 8 9202 1145.

,Accepted 11 April 2009.

References 

  1. Yates AA. Using criteria to establish nutrient intake values (NIVs). Food Nutr Bull. 2007;28(March (Suppl. 1 International)):S38–S50
  2. Kril JJ. Neuropathology of thiamine deficiency disorders. Metab Brain Dis. 1996;11(March (1)):9–17
  3. Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357(July (3)):266–268
  4. el-Ghorab M, Capone A, Underwood BA, Hatchell D, Friend J, Thoft RA. Response of ocular surface epithelium to corneal wounding in retinol-deficient rabbits. Invest Ophthalmol Vis Sci. 1988;29(November (11)):1671–1676
  5. Berger MM. Antioxidant micronutrients in major trauma and burns: evidence and practice. Nutr Clin Pract. 2006;21(October (5)):438–449
  6. Meyer NA, Muller MJ, Herndon DN. Nutrient support of the healing wound. New Horiz. 1994;2(2):202–214May
  7. Gudaviciene D, Rimdeika R, Adamonis K. Nutrition of burned patients. Medicina (Kaunas). 2004;40(1):1–8
  8. Heyland DK: . Nutritional support in the critically ill patient: a critical review of the evidence. Crit Care Clin. 1998;14:423–440
  9. Hart DW, Wolf SE, Herndon DN, Chinkes DL, Lal SO, Obeng MK, et al. Energy expenditure and caloric balance after burn: increased feeding leads to fat rather than lean mass accretion. Ann Surg. 2002;235(January (1)):152–161
  10. Hart DW, et al. Effects of early excision and aggressive enteral feeding on hypermetabolism, catabolism, and sepsis after severe burn. J Trauma. 2003;54(4):755–761[discussion 761-4]
  11. Dominioni L, et al. Enteral feeding in burn hypermetabolism: nutritional and metabolic effects of different levels of calorie and protein intake. JPEN J Parenter Enteral Nutr. 1985;9(3):269–279
  12. Noordenbos J, et al. Enteral nutritional support and wound excision and closure do not prevent postburn hypermetabolism as measured by continuous metabolic monitoring. J Trauma. 2000;49(4):667–671[discussion 671-2]
  13. Peck MD, et al. Early enteral nutrition does not decrease hypermetabolism associated with burn injury. J Trauma. 2004;57(6):1143–1149
  14. Sakurai Y, et al. Stimulation of muscle protein synthesis by long-term insulin infusion in severely burned patients. Ann Surg. 1995;222(3):283–294294-7
  15. Gore DC, et al. Hyperglycemia exacerbates muscle protein catabolism in burn-injured patients. Crit Care Med. 2002;30(11):2438–2442
  16. Garrel DR, et al. Improved clinical status and length of care with low-fat nutrition support in burn patients. JPEN J Parenter Enteral Nutr. 1995;19(6):482–491
  17. Hart DW, et al. Efficacy of a high-carbohydrate diet in catabolic illness. Crit Care Med. 2001;29(7):1318–1324
  18. Gottschlich MM, et al. Differential effects of three enteral dietary regimens on selected outcome variables in burn patients. JPEN J Parenter Enteral Nutr. 1990;14(3):225–236
  19. Jobin N, Garrel DR, Champoux J, Bernier . J Improved immune functions with administration of a low-fat diet in a burn animal model. Cell Immunol. 2000;206(December (2)):71–84
  20. Lonsdale D. Thiamine involved in metabolism. A review of the biochemistry, metabolism and clinical benefits of thiamin(e) and Its derivatives. eCAM. 2006;3(1):49–59
  21. Lonsdale D. Hypothesis and case reports: possible thiamine deficiency. J Am Coll Nutr. 1990;9:13–17
  22. Lonsdale D, Shamberger RJ. Red cell transketolase as an indicator of nutritional deficiency. Am J Clin Nutr. 1980;33:205–211
  23. Yarmush DM, Macdonald AD, Foy BD, Berthiaume F, Tompkins RG, Yarmush ML. Cutaneous burn injury alters relative tricarboxylic acid cycle fluxes in rat liver. J Burn Care Rehabil. 1999;20(4):292–302
  24. Wolfe RR, Jahoor F, Herndon DN, Miyoshi H. Isotopic evaluation of the metabolism of pyruvate and related substrates in normal adult volunteers and severely burned children effect of dichloroacetate and glucose infusion. Surgery. 1991;110(1):54–67
  25. Newman JJ, Strome DR, Goodwin CW, Mason A, Pruitt BA. Altered muscle metabolism in rats after thermal injury. Metabolism. 1982;31(12):1229–1233
  26. D. Talwar, H. Davidson, J. Cooney, D. St. J O’Reilly, Vitamin B1 Status assessed by direct measurement of thiamin pyrophosphate in erythrocytes or whole blood by HPLC: comparison with erythrocyte transketolase activation assay. Clin Chem 2000;46(5):704–10.
  27. O’Brien D, Ibbott FA, Rodgerson DO. Laboratory manual of pediatric micro-biochemical techniques. Hoeber medical division. New York, NY: Harper & Row; 1968;
  28. Abramson D, Scalea TM, Hitchcock R, Trooskin SZ, Henry SM, Greenspan J. Lactate clearance and survival following injury. J Trauma. 1993;35:584–589
  29. Claridge JA, Crabtree TD, Pelletier SJ, Butler K, Sawyer RG, Young JS. Persistent occult hypoperfusion is associated with a significant increase in infection rate and mortality in major trauma patients. J Trauma. 2000;48:8–14

PII: S0305-4179(09)00114-4

doi: 10.1016/j.burns.2009.04.012

Burns
Volume 36, Issue 2 , Pages 261-269 , March 2010

Article Tools

* Image Usage & Resolution