Burns
Volume 36, Issue 6 , Pages 751-758 , September 2010

Use of Acticoat™ dressings in burns: What is the evidence?

  • Roba Khundkar

      Affiliations

    • Department of Plastic and Reconstructive Surgery, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 07931762703.
    • ,
  • Claudia Malic

      Affiliations

    • Department of Plastic & Reconstructive Surgery, Frenchay Hospital, Frenchay Park Road, Bristol, BS16 1LE, UK
    • ,
  • Tim Burge

      Affiliations

    • Department of Plastic & Reconstructive Surgery, Frenchay Hospital, Frenchay Park Road, Bristol, BS16 1LE, UK

,Accepted 1 April 2009.

References 

  1. Bostock J, Riley HT. The Natural History. Pliny the Elder. London: Taylor and Francis; 1855;
  2. Childress BB, Bercell SS, Nelson PR, Lee WA, Ozaki CK. Impact of an absorbent silver-eluting dressing system on lower extremity revascularization wound complications. Ann Vasc Surg. 2007;21(5):598–602
  3. Merone A, Sergio M, Vanessa T, Daniela C, Giovanni S. The use of acticoat in the treatment of pediatric burns. Burns. 2007;33S:SI–SI72
  4. Tredget EE, Shankowsky HA, Groenveld A, Burrell R. A matched-pair, randomized study evaluating the efficacy and safety of Acticoat silver-coated dressing for the treatment of burn wounds. J Burn Care Rehabil. 1998;19(6):531–537
  5. Fong J, Wood F, Fowler B. A silver coated dressing reduces the incidence of early burn wound cellulitis and associated costs of inpatient treatment: comparative patient care audits. Burns. 2005;31(5):562–567
  6. Cuttle L, Naidu S, Mill J, Hoskins W, Das K, Kimble RM. A retrospective cohort study of Acticoat versus Silvazine in a paediatric population. Burns. 2007;33(6):701–707
  7. Huang Y, Li X, Liao Z, Zhang G, Liu Q, Tang J, et al. A randomized comparative trial between Acticoat and SD-Ag in the treatment of residual burn wounds, including safety analysis. Burns. 2007;33(2):161–166
  8. Rustogi R, Mill J, Fraser JF, Kimble RM. The use of Acticoat in neonatal burns. Burns. 2005;31(7):878–882
  9. Ulkur E, Oncul O, Karagoz H, Yeniz H, Celikoz B. Comparison of silver-coated dressing (Acticoat), chlorhexidine acetate 0.5% (Bactigrass), and silver sulfadiazine 1% (Silverdin) for topical antibacterial effect in Pseudomonas aeruginosa-contaminated, full-skin thickness burn wounds in rats. J Burn Care Rehabil. 2005;26(5):430–433
  10. Fraser JF, Cuttle L, Kempf M, Kimble RM. Cytotoxicity of topical antimicrobial agents used in burn wounds in Australasia. ANZ J Surg. 2004;74(3):139–142
  11. Marazzi M, De Angelis A, Ravizza A, Ordanini MN, Falcone L, Chiaratt A, et al. Successful management of deep facial burns in a patient with extensive third-degree burns: the role of a nanocrystalline silver dressing in facilitating resurfacing. Int Wound J. 2007;4(1):8–14
  12. Wright JB, Lam K, Hansen D, Burrel RE. Efficacy of topical silver against fungal burn wound pathogens. Am J Infect Control. 1999;27(4):344–350
  13. Wright JB, Lam K, Buret AG, Olson ME, Burrell RE. Early healing events in a porcine model of contaminated wounds: effects of nanocrystalline silver on matrix metalloproteinases, cell apoptosis, and healing. Wound Repair Regen. 2002;10(3):141–151
  14. Mazurak VC, Burrell RE, Tredget EE, Ciandinin MT, Field CT. The effect of treating infected skin grafts with Acticoat on immune cells. Burns. 2007;33(1):52–58
  15. Demling RH, DeSanti MDL. The rate of re-epithelialization across meshed skin grafts is increased with exposure to silver. Burns. 2002;28(3):264–266
  16. Burd A, Kwok CH, Hung SC, Chan HS, Gu H, Lam KW, et al. A comparative study of the cytotoxicity of silver-based dressings in monolayer cell, tissue explant, and animal models. Wound Repair Regen. 2007;15(1):94–104
  17. Innes ME, Umraw N, Fish JS, Gomez M, Cartotto RC. The use of silver coated dressings on donor site wounds: a prospective, controlled matched pair study. Burns. 2001;27(6):621–627
  18. Bhol KC, Alroy J, Schechter PJ. Anti-inflammatory effect of topical nanocrystalline silver cream on allergic contact dermatitis in a guinea pig model. Clin Exp Dermatol. 2004;29(3):282–287
  19. Poon VK, Burd A. In vitro cytotoxity of silver: implication for clinical wound care. Burns. 2004;30(2):140–147
  20. Fraser JF, Bodman J, Sturgess R, Faoagali J, Kimble RM. An in vitro study of the anti-microbial efficacy of a 1% silver sulphadiazine and 0.2% chlorhexidine digluconate cream, 1% silver sulphadiazine cream and a silver coated dressing. Burns. 2004;30(1):35–41
  21. Vlachou E, Chipp E, Shale E, Wilson Y, Papini R, Moiemen N. The safety of nanocrystalline silver dressings on burns: a study of systemic silver absorption. Burns. 2007;33(8):979–985
  22. Brooks P, Phang KL, Moazzam A. Nanocrystalline silver (Acticoat) for itch relief in the burns patient. ANZ J Surg. 2007;77(9):797
  23. Castellano JJ, Shafii SM, Ko F, Donate G, Wright TE, Mannari RJ, et al. Comparative evaluation of silver-containing antimicrobial dressings and drugs. Int Wound J. 2007;4(2):114–122
  24. Le Duc Q, Breetveld M, Middelkoop E, Scheper RJ, Ulrich MMW, Gibb S. A cytotoxic analysis of antiseptic medication on skin substitutes and autograft. Br J Dermatol. 2007;157(1):33–40
  25. Percival SL, Bowler P, Dolman J. Susceptibility of silver resistant bacteria to silver containing wound dressings. Burns. 2007;33S:S1–S172
  26. Burd A, Zeng A. Changing perspectives in paediatric burns care. Hong Kong J Paediatr. 2003;8:272–282
  27. O’Neill MA, Vine GJ, Beezer AE, Bishop AH, Hadgraft J, Labetoulle C. Antimicrobial properties of silver-containing wound dressings: a microcalorimetric study. Int J Pharm. 2003;263(1–2):61–68
  28. Holder IA, Durkee P, Supp AP, Boyce ST. Assessment of a silver-coated barrier dressing for potential use with skin grafts on excised burns. Burns. 2003;29(5):445–448
  29. Burrell RE, Heggers JP, James-Davis G, Wright JB. Efficacy of silver-coted dressings as bacterial barriers in a rodent sepsis model. Wounds. 1999;11(4):64–71

PII: S0305-4179(09)00124-7

doi: 10.1016/j.burns.2009.04.008

Burns
Volume 36, Issue 6 , Pages 751-758 , September 2010

Article Tools

* Image Usage & Resolution